| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50302828 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795752 (CHEMBL1936639) |
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| IC50 | 280±n/a nM |
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| Citation |  Wang, Y; Fu, Z; Schmitt, M; Wang, X; Shen, W; Rickel, E; Martin, T; Budelsky, A; Marshall, D; Collins, T; Tang, HL; Medina, JC; Liu, JJ Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. Bioorg Med Chem Lett22:367-70 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50302828 |
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| n/a |
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| Name | BDBM50302828 |
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| Synonyms: | 2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulfonamido)phenoxy)-3-methoxyphenyl)acetic acid | CHEMBL589973 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26Cl2N2O7S |
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| Mol. Mass. | 581.465 |
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| SMILES | CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 |
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| Structure | 
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