| Reaction Details |
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 | Report a problem with these data |
| Target | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Ligand | BDBM50360767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796575 (CHEMBL1937890) |
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| IC50 | 40±n/a nM |
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| Citation |  Harada, K; Kubo, H; Tanaka, A; Nishioka, K Identification of oxazolidinediones and thiazolidinediones as potent 17ß-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett22:504-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Name: | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Synonyms: | 17-beta-HSD 3 | 17-beta-hydroxysteroid dehydrogenase type 3 | DHB3_MOUSE | Edh17b3 | Hsd17b3 | Testicular 17-beta-hydroxysteroid dehydrogenase | Testosterone 17-beta-dehydrogenase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34345.90 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_796575 |
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| Residue: | 305 |
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| Sequence: | MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAY
SFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLE
IGILVNNVGMLPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNIS
SGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNNKMT
KTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKR
NISNR
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| BDBM50360767 |
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| n/a |
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| Name | BDBM50360767 |
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| Synonyms: | CHEMBL1934493 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12BrNO3S2 |
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| Mol. Mass. | 422.316 |
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| SMILES | COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O |
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| Structure | 
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