| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E synthase |
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| Ligand | BDBM50360819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796762 (CHEMBL1938077) |
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| IC50 | 506±n/a nM |
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| Citation |  Shiro, T; Takahashi, H; Kakiguchi, K; Inoue, Y; Masuda, K; Nagata, H; Tobe, M Synthesis and SAR study of imidazoquinolines as a novel structural class of microsomal prostaglandin E2 synthase-1 inhibitors. Bioorg Med Chem Lett22:285-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E synthase |
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| Name: | Prostaglandin E synthase |
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| Synonyms: | MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1) |
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| Type: | Protein |
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| Mol. Mass.: | 17112.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 152 |
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| Sequence: | MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
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| BDBM50360819 |
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| n/a |
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| Name | BDBM50360819 |
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| Synonyms: | CHEMBL1934797 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H9Br2N3 |
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| Mol. Mass. | 403.071 |
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| SMILES | Brc1ccc2c3nc([nH]c3cnc2c1)-c1ccccc1Br |
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| Structure | 
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