| Reaction Details |
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 | Report a problem with these data |
| Target | Lysine-specific histone demethylase 2 |
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| Ligand | BDBM50346864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797218 (CHEMBL1942533) |
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| Ki | 38000±n/a nM |
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| Citation |  Suzuki, T; Miyata, N Lysine demethylases inhibitors. J Med Chem54:8236-50 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysine-specific histone demethylase 2 |
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| Name: | Lysine-specific histone demethylase 2 |
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| Synonyms: | AOF1 | C6orf193 | Flavin-containing amine oxidase domain-containing protein 1 | KDM1B | KDM1B_HUMAN | LSD2 | Lysine-specific histone demethylase 1B | Lysine-specific histone demethylase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 92112.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_992590 |
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| Residue: | 822 |
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| Sequence: | MATPRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTA
TCPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSN
GKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPE
TSDHCSLPEDLRVLEVSNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRA
AATGNASPGKLEHSKAALSVHVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEY
SRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKG
LINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGR
VWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTID
KRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHL
SNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQC
IDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIE
KIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVAS
VRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYD
IIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF
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| BDBM50346864 |
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| n/a |
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| Name | BDBM50346864 |
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| Synonyms: | CHEMBL1797641 | CHEMBL3104337 | US8765820, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N3O3 |
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| Mol. Mass. | 429.5109 |
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| SMILES | NC1CC1c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1 |
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| Structure | 
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