| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50280480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155000 |
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| IC50 | 2.3±n/a nM |
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| Citation |  Hodgkin, EE; Miller, A; Whittaker, M A partial pharmacophore for the platelet activating factor (PAF) receptor Bioorg Med Chem Lett2:597-602 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50280480 |
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| n/a |
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| Name | BDBM50280480 |
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| Synonyms: | CHEMBL156461 | YM-461 | [4-(3-Phenyl-propyl)-piperazin-1-yl]-((R)-2-pyridin-3-yl-thiazolidin-4-yl)-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N4OS |
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| Mol. Mass. | 396.549 |
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| SMILES | O=C([C@@H]1CSC(N1)c1cccnc1)N1CCN(CCCc2ccccc2)CC1 |
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| Structure | 
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