| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin B |
|---|
| Ligand | BDBM50284776 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_47605 |
|---|
| IC50 | 98±n/a nM |
|---|
| Citation |  Woo, J; Sigeizumi, S; Yamaguchi, K; Sugimoto, K; Kobori, T; Tsuji, T; Kondo, K Peptidyl aldehyde derivatives as potent and selective inhibitors of cathepsin L Bioorg Med Chem Lett5:1501-1504 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin B |
|---|
| Name: | Cathepsin B |
|---|
| Synonyms: | APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 37819.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_63102437 |
|---|
| Residue: | 339 |
|---|
| Sequence: | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
|
|
|
|---|
| BDBM50284776 |
|---|
| n/a |
|---|
| Name | BDBM50284776 |
|---|
| Synonyms: | CHEMBL36904 | Z-Phe-Tyr(Me)-H |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H28N2O6 |
|---|
| Mol. Mass. | 476.521 |
|---|
| SMILES | COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)C(O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
