Reaction Details |
| Report a problem with these data |
Target | Cathepsin B |
---|
Ligand | BDBM50284782 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_47605 |
---|
IC50 | 18±n/a nM |
---|
Citation | Woo, J; Sigeizumi, S; Yamaguchi, K; Sugimoto, K; Kobori, T; Tsuji, T; Kondo, K Peptidyl aldehyde derivatives as potent and selective inhibitors of cathepsin L Bioorg Med Chem Lett5:1501-1504 (1995) Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Cathepsin B |
---|
Name: | Cathepsin B |
Synonyms: | APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1 |
Type: | Enzyme |
Mol. Mass.: | 37819.69 |
Organism: | Homo sapiens (Human) |
Description: | gi_63102437 |
Residue: | 339 |
Sequence: | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
|
|
|
BDBM50284782 |
---|
n/a |
---|
Name | BDBM50284782 |
Synonyms: | CHEMBL418606 | Z-Phe-Leu-H |
Type | Small organic molecule |
Emp. Form. | C23H28N2O5 |
Mol. Mass. | 412.4788 |
SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O |
Structure |
|