| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM22541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_86896 |
|---|
| Ki | 0.180000±n/a nM |
|---|
| Citation |  Khan, M; Yates, SL; Tedford, CE; Kirschbaum, K; Phillips, JG Diastereoselective synthesis of trans-2-(1-triphenylmethyl-1H-imidazol-4-yl)cyclopropanecarboxylic acids: key intermediates for the preparation of potent and chiral histamine H3 receptor agents Bioorg Med Chem Lett7:3017-3022 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 48607.98 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
|
|
|
|---|
| BDBM22541 |
|---|
| n/a |
|---|
| Name | BDBM22541 |
|---|
| Synonyms: | Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide | VUF 9153 | VUF-9153 | VUF9153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17ClN4S |
|---|
| Mol. Mass. | 308.83 |
|---|
| SMILES | NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| |
|---|
| Structure | 
|
|---|
Search and Browse
