| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM50090254 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34103 (CHEMBL649732) |
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| Ki | <40000±n/a nM |
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| Citation |  Gerrard, JA; Prince, MJ; Abell, AD Kinetic characterisation of ene-diol-based inhibitors of alpha-amylase. Bioorg Med Chem Lett10:1575-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMYP_RAT | Amy2 | PA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57186.64 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_34101 |
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| Residue: | 508 |
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| Sequence: | MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPP
NENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGS
GNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDL
ALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRP
FIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVP
TDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNF
QNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFAN
WWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVN
VGSDGKAHFSISNSAEDPFIAIHADSKL
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| BDBM50090254 |
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| n/a |
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| Name | BDBM50090254 |
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| Synonyms: | (R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5H-furan-2-one | CHEMBL39670 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12O6 |
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| Mol. Mass. | 216.188 |
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| SMILES | CC1(C)OC[C@H](O1)c1oc(O)c(O)c1O |
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| Structure | 
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