| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50092284 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41358 |
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| IC50 | 100000±n/a nM |
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| Citation |  Grant, EB; Guiadeen, D; Baum, EZ; Foleno, BD; Jin, H; Montenegro, DA; Nelson, EA; Bush, K; Hlasta, DJ The synthesis and SAR of rhodanines as novel class C beta-lactamase inhibitors. Bioorg Med Chem Lett10:2179-82 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase TEM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31512.33 |
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| Organism: | Enterobacter cloacae |
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| Description: | ChEMBL_41358 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
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| BDBM50092284 |
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| n/a |
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| Name | BDBM50092284 |
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| Synonyms: | 5-[(E)-3-(5-Nitro-furan-2-yl)-prop-2-en-(Z)-ylidene]-2-thioxo-thiazolidin-4-one | CHEMBL69612 | cid_5335985 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H6N2O4S2 |
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| Mol. Mass. | 282.296 |
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| SMILES | [O-][N+](=O)c1ccc(C=CC=C2SC(S)=NC2=O)o1 |w:7.6,9.8,c:13| |
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| Structure | 
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