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TargetFructose-1,6-bisphosphatase 1 (FBPase)
LigandBDBM3556
Substrate/Competitorn/a
Meas. Tech.ChEBML_157940
IC50>10000±n/a nM
Citation Wright SWHageman DLMcClure LDCarlo AATreadway JLMathiowetz AMWithka JMBauer PH Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines. Bioorg Med Chem Lett 11:17-21 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Fructose-1,6-bisphosphatase 1 (FBPase)
Name:Fructose-1,6-bisphosphatase
Synonyms:Fructose-1,6-bisphosphatase
Type:Protein
Mol. Mass.:36781.07
Organism:Sus scrofa (Pig)
Description:Liver FBPase (P00636)
Residue:338
Sequence:
MTDQAAFDTNIVTLTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGI
AGSTNVTGDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDKNAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSIGTIFGIYRKNSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMVN
GVNCFMLDPAIGEFILVDRDVKIKKKGSIYSINEGYAKEFDPAITEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFMYPANKKSPKGKLRLLYECNPMAYVMEKAGGLATTGK
EAVLDIVPTDIHQRAPIILGSPEDVTELLEIYQKHAAK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM3556
n/a
NameBDBM3556
Synonyms:4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline | CHEMBL1204199 | CHEMBL35820 | N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine | PD153035 Analog | PD153035 Analog 56
TypeSmall organic molecule
Emp. Form.C18H18BrN3O2
Mol. Mass.388.258
SMILESCCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC
Structure
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