| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuraminidase |
|---|
| Ligand | BDBM50097651 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_200639 |
|---|
| IC50 | 420±n/a nM |
|---|
| Citation |  Wyatt, PG; Coomber, BA; Evans, DN; Jack, TI; Fulton, HE; Wonacott, AJ; Colman, P; Varghese, J Sialidase inhibitors related to zanamivir. Further SAR studies of 4-amino-4H-pyran-2-carboxylic acid-6-propylamides. Bioorg Med Chem Lett11:669-73 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuraminidase |
|---|
| Name: | Neuraminidase |
|---|
| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 50124.14 |
|---|
| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
|---|
| Description: | P03468 |
|---|
| Residue: | 454 |
|---|
| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
|
|
|
|---|
| BDBM50097651 |
|---|
| n/a |
|---|
| Name | BDBM50097651 |
|---|
| Synonyms: | (4S,5R,6R)-5-Acetylamino-6-dipropylcarbamoyl-4-ethylamino-5,6-dihydro-4H-pyran-2-carboxylic acid | CHEMBL422016 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H29N3O5 |
|---|
| Mol. Mass. | 355.4293 |
|---|
| SMILES | CCCN(CCC)C(=O)[C@@H]1OC(=C[C@H](NCC)[C@H]1NC(C)=O)C(O)=O |c:11| |
|---|
| Structure | 
|
|---|
Search and Browse
