| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
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| Ligand | BDBM50099325 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_33379 |
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| Ki | 67±n/a nM |
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| Citation |  Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien. Bioorg Med Chem Lett11:1119-21 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2B adrenergic receptor |
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| Name: | Alpha-2B adrenergic receptor |
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| Synonyms: | ADA2B_RAT | Adra2b | Adrenergic receptor alpha | Adrenergic receptor alpha-2 | Alpha-2B adrenergic receptor | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | adrenergic Alpha2B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50379.83 |
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| Organism: | NEONATAL RAT |
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| Description: | adrenergic Alpha2B ADRA2B NEONATAL RAT::P19328 |
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| Residue: | 453 |
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| Sequence: | MSGPTMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLA
AADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVS
RALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPRGLPQCELNQEAWYILA
SSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQPVAGGVPTSAKVP
TLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPTWSALPRSGQGQKKGTSGATAE
EGDEEDEEEVEECEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASGQWW
RRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYC
NSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW
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| BDBM50099325 |
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| n/a |
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| Name | BDBM50099325 |
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| Synonyms: | 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-m-tolyl-1H-thieno[2,3-d]pyrimidine-2,4-dione | A-123189 | CHEMBL13856 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N4O3S |
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| Mol. Mass. | 476.591 |
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| SMILES | COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1 |
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| Structure | 
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