Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50114970 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_79805 |
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IC50 | 4850±n/a nM |
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Citation | Murphy, PV; O'Brien, JL; Gorey-Feret, LJ; Smith, AB Structure-based design and synthesis of HIV-1 protease inhibitors employing beta-D-mannopyranoside scaffolds. Bioorg Med Chem Lett12:1763-6 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50114970 |
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n/a |
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Name | BDBM50114970 |
Synonyms: | (6R,7R,8aR)-8-Benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol | CHEMBL50700 |
Type | Small organic molecule |
Emp. Form. | C21H24O6 |
Mol. Mass. | 372.4117 |
SMILES | CO[C@@H]1OC2COC(O[C@H]2C(OCc2ccccc2)[C@H]1O)c1ccccc1 |
Structure |
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