| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50118929 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_33949 (CHEMBL649574) |
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| IC50 | 140000±n/a nM |
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| Citation |  Ogawa, S; Mori, M; Takeuchi, G; Doi, F; Watanabe, M; Sakata, Y Convenient synthesis and evaluation of enzyme inhibitory activity of several N-alkyl-, N-phenylalkyl, and cyclic isourea derivatives of 5a-carba-alpha-DL-fucopyranosylamine. Bioorg Med Chem Lett12:2811-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53690.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_34088 |
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| Residue: | 466 |
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| Sequence: | MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
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| BDBM50118929 |
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| n/a |
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| Name | BDBM50118929 |
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| Synonyms: | (6R,7S,7aS)-2-Butylamino-5-methyl-3a,4,5,6,7,7a-hexahydro-benzooxazole-6,7-diol | CHEMBL97066 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H22N2O3 |
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| Mol. Mass. | 242.3147 |
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| SMILES | CCCCNC1=NC2CC(C)C(O)C(O)C2O1 |t:5| |
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| Structure | 
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