| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50120143 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145476 |
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| Ki | 7430±n/a nM |
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| Citation |  Wu, WL; Caplen, MA; Domalski, MS; Zhang, H; Fawzi, A; Burnett, DA Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands. Bioorg Med Chem Lett12:3157-60 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50120143 |
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| n/a |
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| Name | BDBM50120143 |
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| Synonyms: | C-[(R)-C-{(S)-1-[Bis-(4-fluoro-phenyl)-methyl]-azetidin-2-yl}-C-(3-chloro-phenyl)]-methylamine | CHEMBL321462 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21ClF2N2 |
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| Mol. Mass. | 398.876 |
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| SMILES | N[C@@H]([C@@H]1CCN1C(c1ccc(F)cc1)c1ccc(F)cc1)c1cccc(Cl)c1 |
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| Structure | 
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