| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50109019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_62080 |
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| Ki | 5.8±n/a nM |
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| Citation |  Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH New generation dopaminergic agents. Part 8: heterocyclic bioisosteres that exploit the 7-OH-2-(aminomethyl)chroman D(2) template. Bioorg Med Chem Lett12:271-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50109019 |
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| n/a |
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| Name | BDBM50109019 |
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| Synonyms: | Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazol-8-ylmethyl)-amine | CHEMBL313851 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18F3N3O |
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| Mol. Mass. | 361.3609 |
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| SMILES | FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 |
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| Structure | 
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