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TargetImmunoglobulin epsilon Fc receptor
LigandBDBM50132449
Substrate/Competitorn/a
Meas. Tech.ChEBML_163803
EC50 5600±n/a nM
Citation Lai JYCox PJPatel RSadiq SAldous DJThurairatnam SSmith KWheeler DJagpal SParveen SFenton GHarrison TKMcCarthy CBamborough P Potent small molecule inhibitors of spleen tyrosine kinase (Syk). Bioorg Med Chem Lett 13:3111-4 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Immunoglobulin epsilon Fc receptor
Name:Immunoglobulin epsilon Fc receptor
Synonyms:BLAST-2 | CD_antigen=CD23 | Fc-epsilon-RII | Immunoglobulin E-binding factor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor
Type:PROTEIN
Mol. Mass.:36461.84
Organism:Homo sapiens (Human)
Description:ChEMBL_88888
Residue:321
Sequence:
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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  Blast E-value cutoff:
BDBM50132449
n/a
NameBDBM50132449
Synonyms:3-((1-(4-morpholino-4-oxobutyl)-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide | 3-[1-[1-(4-Morpholin-4-yl-4-oxo-butyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide | CHEMBL322152
TypeSmall organic molecule
Emp. Form.C25H26N4O5S
Mol. Mass.494.563
SMILESNS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(CCCC(=O)N4CCOCC4)c4ccccc34)c2c1
Structure
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