| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Integrase |
|---|
| Ligand | BDBM50056891 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_90870 (CHEMBL699303) |
|---|
| IC50 | 700±n/a nM |
|---|
| Citation |  Mustata, GI; Brigo, A; Briggs, JM HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett14:1447-54 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Integrase |
|---|
| Name: | Integrase |
|---|
| Synonyms: | Human immunodeficiency virus type 1 integrase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32231.48 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | ChEMBL_90865 |
|---|
| Residue: | 288 |
|---|
| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
|
|
|
|---|
| BDBM50056891 |
|---|
| n/a |
|---|
| Name | BDBM50056891 |
|---|
| Synonyms: | 2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydrazide | 2-hydroxybenzoic acid 2-(2-hydroxybenzoyl)hydrazide | CHEMBL36303 | cid_65303 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H12N2O4 |
|---|
| Mol. Mass. | 272.2561 |
|---|
| SMILES | Oc1ccccc1C(=O)NNC(=O)c1ccccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
