| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50366990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152417 |
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| IC50 | 195000±n/a nM |
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| Citation |  Davis, DP; Borchardt, RT; Grunewald, GL Importance of the aromatic ring in adrenergic amines. 6. Nonaromatic analogues of phenylethanolamine as inhibitors of phenylethanolamine N-methyltransferase: role of pi-electronic and steric interactions. J Med Chem24:12-6 (1981) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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| BDBM50366990 |
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| n/a |
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| Name | BDBM50366990 |
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| Synonyms: | CHEMBL1202589 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H21NO |
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| Mol. Mass. | 195.3012 |
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| SMILES | NCC(O)[C@@]12CC3C[C@@H](C[C@H](C3)C1)C2 |r,TLB:7:8:11.6.5:12,THB:7:6:13.8.9:12| |
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| Structure | 
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