Reaction Details |
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Target | Adenylate kinase 2, mitochondrial |
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Ligand | BDBM50367071 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_32036 |
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Ki | 4700000±n/a nM |
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Citation | Hampton, A; Picker, D; Nealy, KA; Maeda, M Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 4. Interactions of adenosine 5'-triphosphate derivatives with adenylate kinases from Escherichia coli and rat tissues. J Med Chem25:382-6 (1982) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Adenylate kinase 2, mitochondrial |
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Name: | Adenylate kinase 2, mitochondrial |
Synonyms: | ADK2 | AK 2 | AK2 | ATP-AMP transphosphorylase 2 | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | KAD2_HUMAN |
Type: | PROTEIN |
Mol. Mass.: | 26480.98 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_32036 |
Residue: | 239 |
Sequence: | MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
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BDBM50367071 |
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n/a |
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Name | BDBM50367071 |
Synonyms: | CHEMBL607736 |
Type | Small organic molecule |
Emp. Form. | C23H33N6O15P3 |
Mol. Mass. | 726.4606 |
SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)OC([C@@H]1O)n1cnc2c(NCCCCCNC(=O)OCc3ccccc3)ncnc12 |r| |
Structure |
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