Reaction Details |
| Report a problem with these data |
Target | GTP:AMP phosphotransferase AK3, mitochondrial |
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Ligand | BDBM50367047 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_32204 (CHEMBL648983) |
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Ki | 24000000±n/a nM |
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Citation | Hampton, A; Kappler, F; Picker, D Species- or isozyme-specific enzyme inhibitors. 4. Design of a two-site inhibitor of adenylate kinase with isozyme selectivity. J Med Chem25:638-44 (1982) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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GTP:AMP phosphotransferase AK3, mitochondrial |
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Name: | GTP:AMP phosphotransferase AK3, mitochondrial |
Synonyms: | AK 3 | Adenylate kinase 3 | Adenylate kinase 3 alpha like 1 | Adenylate kinase 3 alpha-like 1 | Ak3 | Ak3l1 | Akl3l | GTP:AMP phosphotransferase mitochondrial | KAD3_RAT |
Type: | PROTEIN |
Mol. Mass.: | 25443.58 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_1340551 |
Residue: | 227 |
Sequence: | MGASGRLLRAVIMGAPGSGKGTGSSRITKHFELKHLSSGDLLRQNMLQGTEIAVLAKSFI
DQGKLIPDDDMTRLALHELKNLTQCSWLLDGFPRTLPQAEALDRVYQIDTVINLNVPFEV
IKLRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQT
EPVLQYYQKKGVLETFSGTETNKIRPHVYSFLQMKVPETIQKASVTP
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BDBM50367047 |
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n/a |
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Name | BDBM50367047 |
Synonyms: | CHEMBL2368667 |
Type | Small organic molecule |
Emp. Form. | C12H17N5NaO7PS |
Mol. Mass. | 429.321 |
SMILES | [Na+].CCSc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O |r| |
Structure |
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