| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50028588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_123830 (CHEMBL734268) |
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| Ki | 28000000±n/a nM |
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| Citation |  Hampton, A; Chawla, RR; Kappler, F Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes. J Med Chem25:644-9 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_RAT | Thymidine kinase | Tk-1 | Tk1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 13514.16 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_208200 |
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| Residue: | 121 |
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| Sequence: | MSYINLPTVLPISPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSNSFSTHDRNTMDALPACMLKDVAQEALGVAVIGIDEGQFFPDIVDFCETMANTGKTVI
V
|
|
|
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| BDBM50028588 |
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| n/a |
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| Name | BDBM50028588 |
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| Synonyms: | 1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-3,5-dimethyl-1H-pyrimidine-2,4-dione | 3-methylthymidine | CHEMBL160884 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N2O5 |
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| Mol. Mass. | 256.2551 |
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| SMILES | Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n(C)c1=O |r| |
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| Structure | 
|
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