| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50027088 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146641 (CHEMBL754925) |
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| EC50 | 500±n/a nM |
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| Citation |  Burke, TR; Bajwa, BS; Jacobson, AE; Rice, KC; Streaty, RA; Klee, WA Probes for narcotic receptor mediated phenomena. 7. Synthesis and pharmacological properties of irreversible ligands specific for mu or delta opiate receptors. J Med Chem27:1570-4 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50027088 |
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| n/a |
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| Name | BDBM50027088 |
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| Synonyms: | CHEMBL291099 | N-(1-{2-[4-(2-Bromo-acetylamino)-phenyl]-ethyl}-piperidin-4-yl)-N-phenyl-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30BrN3O2 |
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| Mol. Mass. | 472.418 |
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| SMILES | CCC(=O)N(C1CCN(CCc2ccc(NC(=O)CBr)cc2)CC1)c1ccccc1 |
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| Structure | 
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