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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50027090 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_148541 | ||
| EC50 | 70±n/a nM | ||
| Citation |  Burke, TR; Bajwa, BS; Jacobson, AE; Rice, KC; Streaty, RA; Klee, WA Probes for narcotic receptor mediated phenomena. 7. Synthesis and pharmacological properties of irreversible ligands specific for mu or delta opiate receptors. J Med Chem27:1570-4 (1985) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44503.11 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. | ||
| Residue: | 398 | ||
| Sequence: |
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| BDBM50027090 | |||
| n/a | |||
| Name | BDBM50027090 | ||
| Synonyms: | 1N-(11-hydroxy-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11,18-tetraen-16-yl)-2-bromoacetamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H25BrN2O4 | ||
| Mol. Mass. | 461.349 | ||
| SMILES | CO[C@]12C=C[C@@]3(C[C@@H]1NC(=O)CBr)C1Cc4ccc(O)c5O[C@@H]2C3(CCN1C)c45 |wD:22.22,5.4,7.8,2.1,c:3,TLB:20:28:5:26.24.25,27:26:5:28.15.14,THB:4:5:28.15.14:26.24.25,(18.84,-22.1,;18.86,-20.54,;18.08,-19.25,;16.74,-18.47,;17.89,-17.37,;16.54,-16.6,;18.08,-16.63,;18.84,-17.9,;20.39,-17.9,;21.51,-18.99,;21.12,-20.49,;23.01,-18.57,;24.11,-19.65,;15.82,-15.24,;14.3,-15.2,;13.5,-16.53,;11.97,-16.5,;11.17,-17.76,;11.92,-19.12,;11.11,-20.42,;13.47,-19.15,;14.89,-20.09,;16.51,-19.22,;15.77,-17.87,;15.57,-16.5,;14.86,-15.77,;15.8,-13.68,;17.15,-12.89,;14.25,-17.84,)| | ||
| Structure | 
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