Reaction Details | |||
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Target | Delta-type opioid receptor | ||
Ligand | BDBM50021258 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_146763 | ||
IC50 | 84±n/a nM | ||
Citation | Archer, S; Michael, J; Osei-Gyimah, P; Seyed-Mozaffari, A; Zukin, RS; Maneckjee, R; Simon, EJ; Gioannini, TL Hybromet: a ligand for purifying opioid receptors. J Med Chem28:1950-3 (1986) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Delta-type opioid receptor | |||
Name: | Delta-type opioid receptor | ||
Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 40465.04 | ||
Organism: | Rattus norvegicus (rat) | ||
Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. | ||
Residue: | 372 | ||
Sequence: |
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BDBM50021258 | |||
n/a | |||
Name | BDBM50021258 | ||
Synonyms: | 4-(4-allyloxyphenyl)-2-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11,18-tetraen-16-yl)-2-butanol | CHEMBL59280 | ||
Type | Small organic molecule | ||
Emp. Form. | C34H41NO5 | ||
Mol. Mass. | 543.693 | ||
SMILES | COc1ccc2CC3N(C)CCC45[C@@H](Oc1c24)[C@@]1(OC)C=C[C@@]35C[C@@H]1[C@@](C)(O)CCc1ccc(OCC=C)cc1 |wU:25.32,wD:13.13,22.24,24.30,25.33,17.20,c:23,THB:9:8:22:16.5.6,15:16:22:8.11.10,21:22:16.5.6:8.11.10,(-2.56,-8.78,;-1.02,-8.75,;-.27,-7.4,;-1.07,-6.07,;-.32,-4.74,;1.22,-4.7,;1.96,-3.36,;3.5,-3.34,;4.25,-1.99,;5.58,-1.21,;2.69,-1.98,;2.76,-4.64,;3.53,-5.98,;4.32,-7.3,;2.74,-8.22,;1.27,-7.38,;2.01,-6.03,;5.84,-7.29,;6.45,-8.7,;5.51,-9.92,;5.44,-5.79,;4.67,-6.12,;4.29,-4.65,;5.82,-4.63,;6.6,-5.95,;8.14,-5.93,;8.13,-4.39,;8.13,-7.47,;9.67,-5.93,;10.45,-7.26,;11.99,-7.26,;12.75,-5.91,;14.29,-5.91,;15.07,-7.24,;16.6,-7.23,;17.37,-5.9,;18.91,-5.89,;19.68,-4.56,;14.3,-8.57,;12.76,-8.59,)| | ||
Structure |