| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H2 receptor |
|---|
| Ligand | BDBM50026284 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_85684 |
|---|
| IC50 | 30000±n/a nM |
|---|
| Citation |  Martinez, J; Bali, JP; Magous, R; Laur, J; Lignon, MF; Briet, C; Nisato, D; Castro, B Structure-activity relationships of C-terminal tri- and tetrapeptide fragments that inhibit gastrin activity. J Med Chem28:273-8 (1985) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H2 receptor |
|---|
| Name: | Histamine H2 receptor |
|---|
| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2_RAT | Hrh2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40269.37 |
|---|
| Organism: | RAT |
|---|
| Description: | HISTAMINE H2 HRH2 RAT::P25102 |
|---|
| Residue: | 358 |
|---|
| Sequence: | MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQ
LFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
|
|
|
|---|
| BDBM50026284 |
|---|
| n/a |
|---|
| Name | BDBM50026284 |
|---|
| Synonyms: | 2-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-4-methyl-pentanoylamino}-succinic acid | CHEMBL318221 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H36N4O8 |
|---|
| Mol. Mass. | 532.586 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
