| Reaction Details |
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 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
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| Ligand | BDBM50026333 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152425 |
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| Ki | 20500±n/a nM |
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| Citation |  Houston, DM; Matuszewska, B; Borchardt, RT Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 10. Base- and amino acid modified analogues of S-aristeromycinyl-L-homocysteine. J Med Chem28:478-82 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phenylethanolamine N-methyltransferase |
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| Name: | Phenylethanolamine N-methyltransferase |
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| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
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| Type: | Enzyme |
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| Mol. Mass.: | 30916.97 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 283 |
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| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
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| BDBM50026333 |
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| n/a |
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| Name | BDBM50026333 |
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| Synonyms: | 2-Amino-4-[4-(4-amino-imidazo[4,5-c]pyridin-1-yl)-2,3-dihydroxy-cyclopentylmethylsulfanyl]-butyric acid | CHEMBL444338 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H23N5O4S |
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| Mol. Mass. | 381.45 |
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| SMILES | NC(CCSCC1CC(C(O)C1O)n1cnc2c(N)nccc12)C(O)=O |
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| Structure | 
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