| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Renin |
|---|
| Ligand | BDBM50024167 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_154904 (CHEMBL878421) |
|---|
| IC50 | 600±n/a nM |
|---|
| Citation |  Guégan, R; Diaz, J; Cazaubon, C; Beaumont, M; Carlet, C; Clément, J; Demarne, H; Mellet, M; Richaud, JP; Segondy, D Pepstatin analogues as novel renin inhibitors. J Med Chem29:1152-9 (1987) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Renin |
|---|
| Name: | Renin |
|---|
| Synonyms: | RENI_RAT | Ren | Ren1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44272.67 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_222765 |
|---|
| Residue: | 402 |
|---|
| Sequence: | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGE
FIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYT
ACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG
GSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSL
QLIMQALGVKEKRANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL
ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
|
|
|
|---|
| BDBM50024167 |
|---|
| n/a |
|---|
| Name | BDBM50024167 |
|---|
| Synonyms: | 3-Hydroxy-4-[2-(3-hydroxy-6-methyl-4-{2-[2-(3-methyl-butyrylamino)-3-phenyl-propionylamino]-hexanoylamino}-heptanoylamino)-propionylamino]-6-methyl-heptanoic acid | CHEMBL3142792 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C39H65N5O9 |
|---|
| Mol. Mass. | 747.9615 |
|---|
| SMILES | CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CC(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
