| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM25878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49420 |
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| IC50 | >100000±n/a nM |
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| Citation |  Evans, BE; Rittle, KE; Bock, MG; DiPardo, RM; Freidinger, RM; Whitter, WL; Gould, NP; Lundell, GF; Homnick, CF; Veber, DF Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists. J Med Chem30:1229-39 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor |
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| Type: | n/a |
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| Mol. Mass.: | 48229.77 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 430 |
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| Sequence: | MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRS
SSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLL
SYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSY
SHMSTSAPPP
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| BDBM25878 |
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| n/a |
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| Name | BDBM25878 |
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| Synonyms: | 5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one | CHEMBL13280 | Flunitrazepam | [3H]Rohypnol | [3H]flunitrazepam |
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| Type | radiolabeled ligand |
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| Emp. Form. | C16H12FN3O3 |
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| Mol. Mass. | 313.2832 |
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| SMILES | CN1c2ccc(cc2C(=NCC1=O)c1ccccc1F)[N+]([O-])=O |c:9| |
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| Structure | 
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