Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50018725 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_148839 |
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Ki | 15±n/a nM |
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Citation | Gacel, G; Zajac, JM; Delay-Goyet, P; Daugé, V; Roques, BP Investigation of the structural parameters involved in the mu and delta opioid receptor discrimination of linear enkephalin-related peptides. J Med Chem31:374-83 (1988) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50018725 |
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n/a |
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Name | BDBM50018725 |
Synonyms: | 2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-[(3-methyl-butylcarbamoyl)-methyl]-4-methylsulfanyl-butyramide | CHEMBL338773 |
Type | Small organic molecule |
Emp. Form. | C21H34N4O4S |
Mol. Mass. | 438.584 |
SMILES | CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)NCCC(C)C |
Structure |
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