| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidylate kinase |
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| Ligand | BDBM50367698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_208561 |
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| IC50 | 6000±n/a nM |
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| Citation |  Davies, LC; Stock, JA; Barrie, SE; Orr, RM; Harrap, KR Dinucleotide analogues as inhibitors of thymidine kinase, thymidylate kinase, and ribonucleotide reductase. J Med Chem31:1305-8 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidylate kinase |
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| Name: | Thymidylate kinase |
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| Synonyms: | CDC8 | DTYMK | KTHY_HUMAN | TMPK | TYMK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 23824.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_946051 |
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| Residue: | 212 |
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| Sequence: | MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK
SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP
DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA
SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK
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| BDBM50367698 |
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| n/a |
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| Name | BDBM50367698 |
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| Synonyms: | CHEMBL604405 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H31N7O26P6 |
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| Mol. Mass. | 971.334 |
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| SMILES | Cc1cn(C2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3OC([C@H](O)[C@@H]3O)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O |r| |
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| Structure | 
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