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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50020116 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_62891 | ||
| Ki | 345±n/a nM | ||
| Citation |  Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies. J Med Chem31:1382-92 (1988) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 50931.60 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P61169 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50020116 | |||
| n/a | |||
| Name | BDBM50020116 | ||
| Synonyms: | 4-[4-(6'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-butyl]-4-aza-tricyclo[5.4.2.0*2,6*]tridec-12-ene-3,5-dione;Hydrochloride | CHEMBL412258 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H32ClN5O2 | ||
| Mol. Mass. | 457.996 | ||
| SMILES | Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4CCCCC3C=C4)C2=O)CC1 |c:28,(24.8,-19.6,;24.8,-18.06,;26.15,-17.31,;26.15,-15.77,;24.83,-14.99,;23.51,-15.76,;23.49,-17.3,;22.17,-14.97,;20.83,-15.74,;19.52,-14.97,;19.52,-13.45,;18.2,-12.68,;16.86,-13.45,;15.53,-12.68,;14.2,-13.45,;12.88,-12.68,;12.69,-11.16,;13.85,-10.12,;11.21,-10.83,;10.42,-12.17,;8.88,-12.18,;8.11,-10.84,;6.77,-10.06,;7.54,-8.72,;8.88,-9.49,;10.44,-9.49,;9.11,-10.31,;10.2,-11.38,;11.44,-13.3,;11.15,-14.81,;20.85,-12.66,;22.17,-13.43,)| | ||
| Structure | 
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