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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50020141 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_62891 | ||
| Ki | 1925±n/a nM | ||
| Citation |  Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies. J Med Chem31:1382-92 (1988) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 50931.60 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P61169 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50020141 | |||
| n/a | |||
| Name | BDBM50020141 | ||
| Synonyms: | 4-{4-[4-(6-chloro-3-pyridazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.4.2.02,6.08,11]tridec-12-ene-3,5-dione;Hydrochloride | CHEMBL424409 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30ClN5O2 | ||
| Mol. Mass. | 455.98 | ||
| SMILES | Clc1ccc(nn1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CCC43)C2=O)CC1 |c:22,(16.79,-27.32,;15.48,-26.56,;14.14,-27.32,;12.82,-26.55,;12.82,-25.01,;14.16,-24.25,;15.48,-25.03,;11.5,-24.22,;10.16,-24.99,;8.84,-24.22,;8.85,-22.71,;7.53,-21.94,;6.19,-22.71,;4.85,-21.94,;3.53,-22.71,;2.19,-21.94,;2.03,-20.41,;3.17,-19.38,;.52,-20.08,;-.25,-21.43,;-1.79,-21.44,;-.47,-20.66,;-1.56,-19.57,;-.25,-18.75,;-1.79,-18.75,;-3.13,-17.98,;-3.9,-19.31,;-2.56,-20.09,;.78,-22.56,;.46,-24.06,;10.16,-21.92,;11.51,-22.69,)| | ||
| Structure | 
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