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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50017431 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_62579 | ||
| Ki | 1031±n/a nM | ||
| Citation |  Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents. J Med Chem32:1024-33 (1989) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 50931.60 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P61169 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50017431 | |||
| n/a | |||
| Name | BDBM50017431 | ||
| Synonyms: | 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-3-one; Hydrochloride | CHEMBL552874 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H28ClN5O3S | ||
| Mol. Mass. | 478.007 | ||
| SMILES | Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)S2(=O)=O)CC1 |c:22,(13.95,-8.09,;13.19,-9.44,;13.72,-10.89,;12.72,-12.08,;11.21,-11.81,;10.68,-10.36,;11.66,-9.17,;9.17,-10.08,;8.64,-8.66,;7.12,-8.38,;6.13,-9.56,;4.63,-9.28,;3.64,-10.44,;2.12,-10.15,;1.11,-11.33,;-.41,-11.04,;-1.48,-12.08,;-1.24,-13.61,;-2.86,-11.37,;-2.6,-9.86,;-3.79,-8.88,;-3.38,-10.37,;-4.92,-10.37,;-4.17,-11.69,;-5.49,-10.94,;-6.68,-9.92,;-5.21,-9.4,;-1.06,-9.65,;-2.02,-8.44,;.13,-8.7,;6.66,-11.01,;8.17,-11.27,)| | ||
| Structure | 
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