| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50016978 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58528 |
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| IC50 | >1000±n/a nM |
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| Citation |  New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA The thieno[3,2-c]pyridine and furo[3,2-c]pyridine rings: new pharmacophores with potential antipsychotic activity. J Med Chem32:1147-56 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50016978 |
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| n/a |
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| Name | BDBM50016978 |
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| Synonyms: | 4,4-Dimethyl-1-{4-[4-(1-methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione; hydrochloride | CHEMBL540253 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H33N5O2 |
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| Mol. Mass. | 411.5404 |
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| SMILES | Cn1ccc2c(nccc12)N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 |
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| Structure | 
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