| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxycytidine kinase |
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| Ligand | BDBM50145605 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_53731 (CHEMBL663657) |
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| Ki | 1000000±n/a nM |
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| Citation |  Palomino, E; Meltsner, BR; Kessel, D; Horwitz, JP Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. J Med Chem33:258-63 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxycytidine kinase |
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| Name: | Deoxycytidine kinase |
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| Synonyms: | DCK | DCK_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30510.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1437135 |
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| Residue: | 260 |
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| Sequence: | MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCN
VQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAE
KPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQA
TPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNE
DFKDKYESLVEKVKEFLSTL
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| BDBM50145605 |
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| n/a |
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| Name | BDBM50145605 |
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| Synonyms: | 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one | CHEMBL853 | DDC | DDCYD | Dideoxycytidine | ZALCITABINE |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13N3O3 |
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| Mol. Mass. | 211.2178 |
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| SMILES | Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1 |r| |
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| Structure | 
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