| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50015803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_28532 (CHEMBL640700) |
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| IC50 | 28±n/a nM |
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| Citation |  Sarges, R; Howard, HR; Browne, RG; Lebel, LA; Seymour, PA; Koe, BK 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. J Med Chem33:2240-54 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50015803 |
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| n/a |
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| Name | BDBM50015803 |
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| Synonyms: | (8-Chloro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-cyclohexyl-amine | CHEMBL73478 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15ClF3N5 |
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| Mol. Mass. | 369.772 |
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| SMILES | FC(F)(F)c1nnc2c(NC3CCCCC3)nc3ccc(Cl)cc3n12 |
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| Structure | 
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