| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
|---|
| Ligand | BDBM50009248 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_159775 (CHEMBL763100) |
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| IC50 | 2500±n/a nM |
|---|
| Citation |  Huff, JR HIV protease: a novel chemotherapeutic target for AIDS. J Med Chem34:2305-14 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
|---|
| Name: | Gag-Pol polyprotein [489-587] |
|---|
| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
|---|
| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
|---|
| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
|---|
| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM50009248 |
|---|
| n/a |
|---|
| Name | BDBM50009248 |
|---|
| Synonyms: | (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide(Cerulenin) | CERULENIN | CHEMBL45627 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H17NO3 |
|---|
| Mol. Mass. | 223.2683 |
|---|
| SMILES | C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O |r| |
|---|
| Structure | 
|
|---|
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