| Reaction Details |
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 | Report a problem with these data |
| Target | Pol polyprotein |
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| Ligand | BDBM50004781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_159124 |
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| IC50 | 2200±n/a nM |
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| Citation |  DeCamp, DL; Babé, LM; Salto, R; Lucich, JL; Koo, MS; Kahl, SB; Craik, CS Specific inhibition of HIV-1 protease by boronated porphyrins. J Med Chem35:3426-8 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pol polyprotein |
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| Name: | Pol polyprotein |
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| Synonyms: | Human immunodeficiency virus type 2 pol protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 100453.78 |
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| Organism: | Human immunodeficiency virus 2 |
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| Description: | ChEMBL_159124 |
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| Residue: | 876 |
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| Sequence: | MTGDTPINIFGRNILTALGMSLNLPVARIEPIKITLKPGKDGPRLKQWPLTKEKVEALKE
ICEKMEKEGQLEEAPPTNPYNTPTFAIKKKDKNKWRMLIDFRELNRVTQDFTEIQLGIPH
PAGLAKKKRITVLDVGDAYFSIPLYEDFRPYTAFTLPSVNNVEPGKRYIYKVLPQGWKGS
PAIFQYTMRQILEPFRKANPDVILIQYMDDILIASDRTGLEHDKVVLQLKELLNGLGFST
PEEKFQKDPPFQWMGYELWPTKWKLQKIQLPQKETWTVNDIQKLVGILNWAAQIYPGIKT
KHLCRLIRGKMTLTEEVQWTELAEAELEENRIILDQEQEGHYYQEEKELEATIQKSQDNQ
WTYKIHQEEKILKVGKYAKIKNTHTNGVRLLAQVVQKIGKEALVIWGRIPKFHLPVERET
WEQWWDNYWQVTWIPEWDFVSTPPLVRLTFNLVGDPIPGTETFYTDGSCNRQSKEGKAGY
VTDRGRDKVRVLEQTTNQQAELEAFAMALADSGPKVNIIVDSQYVMGIVASQPTESESRI
VNQIIEDMIKKEAVYVAWIPAHKGIGGNQEVDHLVSQGIRQVLFLEKIEPAQEEHEKYHS
NIKELIHKFGIPQLVARQIVNTCAQCQQKGEAIHGQVNAEIGVWQMDCTHLEGKIIIVAV
HVASGFIEAEVIPQESGRQTALFLLKLASRWPITHLHTDNGPNFTSQEVKMVAWWVGIEQ
SFGVPYNPQSQGVVEAMNHHLKNQISRIREQANTVETIVLMAVHCMNFKRRGGIGDMTPA
ERLINMITTEQEIQFLQRKNSNFKKFQVYYREGRDQLWKGPGELLWKGEGAVIVKVGADI
KVVPRRKAKIIRDYGGRQELDSSPHLEGAREDGEVA
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| BDBM50004781 |
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| n/a |
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| Name | BDBM50004781 |
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| Synonyms: | 3-[18-(2-Carboxy-ethyl)-8,13-bis-(1,2-diacetoxy-ethyl)-3,7,12,17-tetramethyl-22,24-dihydro-porphin-2-yl]-propionic acid;Cu complex | CHEMBL326715 |
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| Type | Small organic molecule |
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| Emp. Form. | C50H44CuN4O12 |
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| Mol. Mass. | 956.45 |
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| SMILES | CC1=C(CCC(O)=O)\C2=C\c3c(CCC(O)=O)c(C)c4\C=C5/N=C(/C=c6/c(C(COC(=O)C7=CC7)OC(=O)C7=CC7)c(C)\c(=C\C1=N2)n6[Cu]n34)C(C)=C5C(COC(=O)C1=CC1)OC(=O)C1=CC1 |c:1,20,48,58,t:8,22,24,32,39,45,66,73| |
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| Structure | 
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