| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50002313 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_216117 |
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| IC50 | 11200±n/a nM |
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| Citation |  Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W Synthesis and pharmacological characterization of 2-(4-chloro-3-hydroxyphenyl)ethylamine and N,N-dialkyl derivatives as dopamine receptor ligands. J Med Chem35:4408-14 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50002313 |
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| n/a |
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| Name | BDBM50002313 |
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| Synonyms: | 2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl-amino}-ethyl)-phenol; hydrobromide | CHEMBL541096 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24ClNO2 |
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| Mol. Mass. | 333.852 |
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| SMILES | CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 |
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| Structure | 
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