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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gastrin/cholecystokinin type B receptor | ||
| Ligand | BDBM50005811 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_48256 | ||
| IC50 | 1080±n/a nM | ||
| Citation |  Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E Amide bond replacements incorporated into CCK-B selective"dipeptoids". J Med Chem35:1472-84 (1992) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Gastrin/cholecystokinin type B receptor | |||
| Name: | Gastrin/cholecystokinin type B receptor | ||
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 49196.59 | ||
| Organism: | MOUSE | ||
| Description: | Cholecystokinin A CCKBR MOUSE::P56481 | ||
| Residue: | 453 | ||
| Sequence: |
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| BDBM50005811 | |||
| n/a | |||
| Name | BDBM50005811 | ||
| Synonyms: | CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid adamantan-2-yl ester;0.5H2O | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H37N3O4 | ||
| Mol. Mass. | 515.6432 | ||
| SMILES | OCC(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |wU:33.36,35.39,29.32,wD:31.40,TLB:27:28:30:33.37.32,THB:34:35:30:33.37.32,34:33:28.35.36:30,32:31:28:33.34.37,(18.97,-6.87,;17.43,-6.97,;16.76,-8.35,;17.62,-9.64,;19.16,-9.51,;20.02,-10.79,;21.54,-10.68,;22.21,-9.28,;21.35,-8.02,;19.81,-8.13,;15.22,-8.47,;14.35,-7.2,;15.03,-5.82,;12.84,-7.31,;11.59,-6.42,;11.75,-4.88,;10.6,-3.86,;11.21,-2.45,;12.75,-2.6,;13.87,-1.55,;15.35,-2.02,;15.67,-3.54,;14.53,-4.57,;13.07,-4.11,;12.06,-8.63,;10.52,-8.61,;9.76,-7.26,;9.73,-9.92,;8.19,-9.89,;8.19,-11.43,;7.17,-12.7,;5.77,-12.14,;4.28,-12.55,;5.46,-11.27,;5.46,-9.8,;6.81,-9.31,;5.75,-10.55,;6.78,-11.77,)| | ||
| Structure | 
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