| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50044695 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_139962 |
|---|
| Ki | 5100±n/a nM |
|---|
| Citation |  Tsukamoto, S; Ichihara, M; Wanibuchi, F; Usuda, S; Hidaka, K; Harada, M; Tamura, T Synthesis and structure-activity studies of a series of spirooxazolidine-2,4-diones: 4-oxa analogues of the muscarinic agonist 2-ethyl-8-methyl-2,8-diazaspiro[4.5]decane-1,3-dione. J Med Chem36:2292-9 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51390.46 |
|---|
| Organism: | RAT |
|---|
| Description: | P08482 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50044695 |
|---|
| n/a |
|---|
| Name | BDBM50044695 |
|---|
| Synonyms: | 3-Allyl-8-methyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione | CHEMBL419451 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H16N2O3 |
|---|
| Mol. Mass. | 224.2563 |
|---|
| SMILES | CN1CCC2(CC1)OC(=O)N(CC=C)C2=O |
|---|
| Structure | 
|
|---|
Search and Browse
