| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium-dependent dopamine transporter |
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| Ligand | BDBM50005534 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61836 (CHEMBL673206) |
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| IC50 | 0.66±n/a nM |
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| Citation |  He, XS; Raymon, LP; Mattson, MV; Eldefrawi, ME; de Costa, BR Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites. J Med Chem36:1188-93 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium-dependent dopamine transporter |
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| Name: | Sodium-dependent dopamine transporter |
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| Synonyms: | DA transporter | Monoamine transporters; Norepininephrine & dopamine | SC6A3_RAT | Slc6a3 | Sodium-dependent dopamine transporter | Sodium-dependent dopamine transporter (DAT) |
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| Type: | Multi-pass membrane protein |
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| Mol. Mass.: | 68749.45 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P23977 |
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| Residue: | 619 |
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| Sequence: | MSKSKCSVGPMSSVVAPAKESNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEAQER
ETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
GQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHC
NNTWNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLT
ACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVD
FYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSG
FVVFSFLGYMAQKHNVPIRDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGID
SAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAG
TSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKLVSPCFLLYVVVVSIV
TFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYATYKFCSLPGSFREKLAYAITPEKDH
QLVDRGEVRQFTLRHWLLL
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| BDBM50005534 |
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| n/a |
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| Name | BDBM50005534 |
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| Synonyms: | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine | 1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-piperidine | 1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-piperidine(BTCP) | 1-[1-(3H-1lambda*4*-Benzo[b]thiophen-2-yl)-cyclohexyl]-piperidine | 3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane | CHEMBL279556 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25NS |
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| Mol. Mass. | 299.474 |
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| SMILES | C1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1 |
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| Structure | 
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