| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50041518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140094 (CHEMBL752971) |
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| EC50 | 4500±n/a nM |
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| Citation |  Botero Cid, MH; Holzgrabe, U; Kostenis, E; Mohr, K; Tränkle, C Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors. J Med Chem37:1439-45 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51688.65 |
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| Organism: | GUINEA PIG |
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| Description: | Cholinergic, muscarinic 0 GUINEA PIG::P06199 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRI
VKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50041518 |
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| n/a |
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| Name | BDBM50041518 |
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| Synonyms: | 4-((E)-{[(2,6-dichlorobenzyl)oxy]imino}methyl)-1-propyl-3yl-(4-(Methoxyimino-methyl)-pyridinium)pyridinium | CHEMBL33656 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24Cl2N4O2 |
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| Mol. Mass. | 459.367 |
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| SMILES | CO\N=C\c1cc[n+](CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1 |
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| Structure | 
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