| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
|---|
| Ligand | BDBM50307921 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_140094 (CHEMBL752971) |
|---|
| EC50 | 4700±n/a nM |
|---|
| Citation |  Botero Cid, MH; Holzgrabe, U; Kostenis, E; Mohr, K; Tränkle, C Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors. J Med Chem37:1439-45 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M2 |
|---|
| Name: | Muscarinic acetylcholine receptor M2 |
|---|
| Synonyms: | ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51688.65 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Cholinergic, muscarinic 0 GUINEA PIG::P06199 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRI
VKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
|
|
|
|---|
| BDBM50307921 |
|---|
| n/a |
|---|
| Name | BDBM50307921 |
|---|
| Synonyms: | (E,E)-1,3-bis[4-[[(2,6-dichlorobenzyloxyl)imino]methyl]pyridinium]propane. dibromide | 1,1'-(propane-1,3-diyl)bis(4-((2,6-dichlorobenzyloxyimino)methyl)pyridinium)bromide | CHEMBL590603 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H26Cl4N4O2 |
|---|
| Mol. Mass. | 604.353 |
|---|
| SMILES | Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
