| Reaction Details |
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 | Report a problem with these data |
| Target | Hydroxyacylglutathione hydrolase, mitochondrial |
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| Ligand | BDBM50039108 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_71297 (CHEMBL686102) |
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| Ki | 3400±n/a nM |
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| Citation |  Murthy, NS; Bakeris, T; Kavarana, MJ; Hamilton, DS; Lan, Y; Creighton, DJ S-(N-aryl-N-hydroxycarbamoyl)glutathione derivatives are tight-binding inhibitors of glyoxalase I and slow substrates for glyoxalase II. J Med Chem37:2161-6 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Hydroxyacylglutathione hydrolase, mitochondrial |
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| Name: | Hydroxyacylglutathione hydrolase, mitochondrial |
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| Synonyms: | GLO2 | GLO2_HUMAN | Glyoxalase II | HAGH | HAGH1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33815.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_71296 |
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| Residue: | 308 |
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| Sequence: | MVVGRGLLGRRSLAALGAACARRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDN
YMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESG
LKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFT
GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAA
IREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREK
DQFKMPRD
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| BDBM50039108 |
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| n/a |
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| Name | BDBM50039108 |
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| Synonyms: | S-(N-Hydroxy-N-(4-chlorophenyl)carbamoyl)glutathione |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20ClN4O8S |
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| Mol. Mass. | 475.881 |
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| SMILES | [NH3+]C(CCC(=O)NC(CSC(=O)N(O)c1ccc(Cl)cc1)C(=O)NCC([O-])=O)C([O-])=O |
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| Structure | 
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