| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50029755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_37201 (CHEMBL650802) |
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| Ki | 30±n/a nM |
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| Citation |  Dalpiaz, A; Bertolasi, V; Borea, PA; Nacci, V; Fiorini, I; Campiani, G; Mennini, T; Manzoni, C; Novellino, E; Greco, G A concerted study using binding measurements, X-ray structural data, and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines toward mitochondrial benzodiazepine receptors. J Med Chem38:4730-8 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo |
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| Type: | Mitochondrion membrane protein |
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| Mol. Mass.: | 18945.84 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competitive binding experiments were performed on rat kidney mitochondrial membranes. |
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| Residue: | 169 |
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| Sequence: | MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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| BDBM50029755 |
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| n/a |
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| Name | BDBM50029755 |
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| Synonyms: | Acetic acid 5-(4-chloro-phenyl)-6-thia-10b-aza-benzo[e]azulen-4-yl ester | CHEMBL116087 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14ClNO2S |
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| Mol. Mass. | 367.849 |
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| SMILES | CC(=O)OC1=C(Sc2ccccc2-n2cccc12)c1ccc(Cl)cc1 |t:4| |
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| Structure | 
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