| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM23412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90698 (CHEMBL702099) |
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| IC50 | 39100±n/a nM |
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| Citation |  Raghavan, K; Buolamwini, JK; Fesen, MR; Pommier, Y; Kohn, KW; Weinstein, JN Three-dimensional quantitative structure-activity relationship (QSAR) of HIV integrase inhibitors: a comparative molecular field analysis (CoMFA) study. J Med Chem38:890-7 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM23412 |
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| n/a |
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| Name | BDBM23412 |
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| Synonyms: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one | 6-Methoxyluteolin | CHEMBL172350 | Eupafolin | cid_5317284 |
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| Type | flavone |
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| Emp. Form. | C16H12O7 |
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| Mol. Mass. | 316.2623 |
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| SMILES | COc1c(O)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 |
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| Structure | 
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