| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 2 |
|---|
| Ligand | BDBM50034501 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106064 (CHEMBL718229) |
|---|
| EC50 | 35000±n/a nM |
|---|
| Citation |  Knöpfel, T; Kuhn, R; Allgeier, H Metabotropic glutamate receptors: novel targets for drug development. J Med Chem38:1417-26 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 2 |
|---|
| Name: | Metabotropic glutamate receptor 2 |
|---|
| Synonyms: | GPRC1B | GRM2 | GRM2_HUMAN | MGLUR2 | Metabotropic glutamate receptor | glutamate receptor, metabotropic 2 precursor | mGlu2 | metabotropic glutamate 2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 95584.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q14416 |
|---|
| Residue: | 872 |
|---|
| Sequence: | MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQ
RLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHI
CPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDY
FARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEK
VGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGAL
ESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQR
DCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYK
DFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTL
DTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADC
GLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKA
SGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARI
FGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLR
CNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIF
YVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAA
RASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
|
|
|
|---|
| BDBM50034501 |
|---|
| n/a |
|---|
| Name | BDBM50034501 |
|---|
| Synonyms: | (S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | (S)-Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic acid | CHEMBL30285 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H6N2O4 |
|---|
| Mol. Mass. | 158.1121 |
|---|
| SMILES | N[C@H](C(O)=O)c1cc(=O)[nH]o1 |
|---|
| Structure | 
|
|---|
Search and Browse
